A 16-year-old girl presents with facial edema and cola-colored urine for 2 weeks. Vital signs show BP 148/92 mmHg, HR 88 bpm, RR 16, temp 37°C, SpO2 98%. Serum creatinine is 1.2 mg/dL (baseline 0.8), and complement C3 is markedly reduced. Urinalysis reveals 3+ proteinuria and dysmorphic RBCs. Renal biopsy demonstrates hypercellular glomeruli with characteristic tram-track appearance on light microscopy. She denies recent upper respiratory infection. Which diagnosis is most likely?
- A)Alport syndrome
- B)Membranoproliferative glomerulonephritisGABARITO
- C)Acute interstitial nephritis
- D)FSGS
- E)Minimal change disease
Explicação
Membranoproliferative glomerulonephritis is characterized by mesangial proliferation and splitting of the glomerular basement membrane, producing a tram-track appearance. It often causes a mixed nephritic-nephrotic presentation and is associated with low compl... Ver explicação completa e trilha adaptativa →