A 3-week-old female infant born to a mother with rubella infection during the first trimester presents with fever (38.2°C), tachycardia (160 bpm), tachypnea (52 breaths/min), and SpO2 98% on room air. Physical examination reveals a continuous machinery murmur, cataracts, sensorineural hearing loss, and hepatosplenomegaly (liver 4 cm below costal margin). Laboratory studies show elevated transaminases. She has not received any cardiac medications. Which cardiac lesion is most commonly associated with congenital rubella syndrome?
- A)Ventricular septal defect
- B)Transposition of the great arteries
- C)Tetralogy of Fallot
- D)Patent ductus arteriosusGABARITO
- E)Atrial septal defect
Explicação
Patent ductus arteriosus is the most characteristic cardiac manifestation of congenital rubella syndrome. The continuous 'machinery' murmur, combined with cataracts, sensorineural hearing loss, hepatosplenomegaly, and intrauterine growth restriction, form the ... Ver explicação completa e trilha adaptativa →