A 63-year-old woman with hypertension (BP 152/94 mmHg, HR 78/min) develops angioedema of the lips and tongue 2 weeks after starting lisinopril. Laboratory studies show normal C1-esterase inhibitor levels. Her physician discontinues lisinopril and prescribes a medication that lowers blood pressure by blocking angiotensin II receptors without inhibiting bradykinin breakdown. SpO2 is 98% on room air. Which of the following medications was most likely prescribed?
- A)LosartanGABARITO
- B)Clonidine
- C)Hydrochlorothiazide
- D)Aliskiren
- E)Spironolactone
Explicação
Losartan is an angiotensin receptor blocker that prevents angiotensin II signaling at the AT1 receptor while avoiding bradykinin accumulation. For that reason, cough and angioedema are less common than with ACE inhibitors. Ver explicação completa e trilha adaptativa →