A 4-year-old boy presents with periorbital and ankle edema. Vital signs: BP 108/62 mmHg, HR 94/min, RR 22/min, Temp 37.2°C, SpO2 98%. Urinalysis reveals 4+ proteinuria with no hematuria. Serum albumin is 1.8 g/dL and total cholesterol is 312 mg/dL. Complement C3 and C4 levels are normal. The child denies recent upper respiratory infection. Which of the following is the most likely diagnosis?
- A)Rapidly progressive glomerulonephritis
- B)Poststreptococcal glomerulonephritis
- C)Minimal change diseaseGABARITO
- D)IgA nephropathy
- E)Acute interstitial nephritis
Explicação
Minimal change disease is the most common cause of nephrotic syndrome in children and presents with edema, heavy selective albuminuria, hypoalbuminemia, and hyperlipidemia. The glomeruli appear normal on light microscopy, but electron microscopy shows diffuse ... Ver explicação completa e trilha adaptativa →