A 60-year-old man with type 2 diabetes mellitus presents with a fasting glucose of 118 mg/dL but postprandial glucose of 320 mg/dL due to irregular meal timing. Vital signs: BP 138/82, HR 88, RR 16, Temp 37°C, SpO2 98%. HbA1c is 7.8%, and fasting C-peptide is 1.8 ng/mL, confirming residual beta-cell function. Physical exam reveals mild truncal obesity with a BMI of 29 kg/m². He denies polyuria or hypoglycemic episodes. His physician prescribes a short-acting insulin secretagogue taken with meals to reduce postprandial glucose excursions. Which drug was most likely prescribed?
- A)RepaglinideGABARITO
- B)Pioglitazone
- C)Insulin glargine
- D)Metformin
- E)Glyburide
Explicação
Repaglinide is a meglitinide with short duration that enhances glucose induced insulin secretion and is especially useful for postprandial hyperglycemia. Its meal associated dosing makes it more flexible than sulfonylureas when meal timing is irregular. Ver explicação completa e trilha adaptativa →