A newborn boy presents with severe respiratory distress (RR 68/min, SpO2 78% on room air) shortly after birth. Prenatal ultrasound demonstrated oligohydramnios and bilaterally enlarged echogenic kidneys with loss of corticomedullary differentiation. Physical examination reveals characteristic flattened facies, micrognathia, and limb deformities. Serum creatinine is 2.8 mg/dL. The mother denies maternal infections or medication use during pregnancy. Which of the following is the most likely diagnosis?
- A)Autosomal dominant polycystic kidney disease
- B)Autosomal recessive polycystic kidney diseaseGABARITO
- C)Wilms tumor
- D)Minimal change disease
- E)Renal cell carcinoma
Explicação
Autosomal recessive polycystic kidney disease is correct. ARPKD presents in infancy with enlarged collecting duct derived cystic kidneys, oligohydramnios, and Potter sequence due to reduced fetal urine production. Congenital hepatic fibrosis is an important as... Ver explicação completa e trilha adaptativa →