A study of a new antihypertensive drug that affects glomerular filtration rate is being conducted. Infusion of drug X causes constriction of the efferent arteriole. After infusion of the drug, the following glomerular values are obtained: hydrostatic pressure of the glomerular capillary (PGC) of 48 mm Hg, oncotic pressure of the glomerular capillary (πGC) of 23 mm Hg, hydrostatic pressure of Bowman's space (PBS) of 10 mm Hg, and oncotic pressure of Bowman's space (πBS) of 0 mm Hg. Which of the following best measures net filtration pressure in this participant?
- A)15 mm HgGABARITO
- B)35 mm Hg
- C)61 mm Hg
- D)0 mm Hg
- E)81 mm Hg
Explicação
Net filtration pressure (NFP) = (PGC - PBS) - (πGC - πBS) = (48 - 10) - (23 - 0) = 38 - 23 = 15 mm Hg. Hydrostatic pressure in the glomerular capillary (PGC) favors filtration, while hydrostatic pressure in Bowman space (PBS) and oncotic pressure in the capill... Ver explicação completa e trilha adaptativa →