A 54-year-old man with hypertension presents with hemoptysis, malaise, and dark urine over two weeks. Vital signs show BP 158/92 mmHg, HR 98 bpm, RR 20/min, Temp 37.2°C, SpO2 98% on room air. Serum creatinine is 2.8 mg/dL. Chest X-ray reveals pulmonary infiltrates. Kidney biopsy demonstrates necrotizing vasculitis of small vessels without granulomatous inflammation. Serology is positive for p-ANCA. He denies respiratory infections. Which diagnosis best explains these findings?
- A)Microscopic polyangiitisGABARITO
- B)Buerger disease
- C)Takayasu arteritis
- D)Polyarteritis nodosa
- E)Granulomatosis with polyangiitis
Explicação
Microscopic polyangiitis is a p ANCA associated small vessel vasculitis that often causes pulmonary capillaritis with hemoptysis and rapidly progressive glomerulonephritis. The absence of granulomas helps distinguish it from granulomatosis with polyangiitis. S... Ver explicação completa e trilha adaptativa →