A 63-year-old male with a 45 pack-year smoking history and COPD presents with progressive cough, unintentional weight loss, and acute confusion. Vital signs show BP 138/82, HR 102, RR 22, SpO2 92% on room air, and temperature 37.2°C. Chest CT reveals a centrally located 4-cm hilar mass. Serum sodium is 121 mEq/L; glucose and renal function are normal. He denies hemoptysis. He takes albuterol and tiotropium regularly. Which of the following is the most likely diagnosis?

  1. A)Bronchiectasis
  2. B)Small cell lung carcinomaGABARITO
  3. C)Pulmonary adenocarcinoma
  4. D)Mesothelioma
  5. E)Pulmonary hamartoma

Explicação

Small cell lung carcinoma is correct. Small cell carcinoma is a central neuroendocrine tumor strongly associated with smoking and is well known for paraneoplastic secretion of antidiuretic hormone, causing hyponatremia and confusion. A central hilar mass in a ... Ver explicação completa e trilha adaptativa →

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