A male newborn presents 2 hours after birth with cyanosis, choking, and coughing during his first feeding. Maternal history includes polyhydramnios. Vital signs show tachypnea (RR 68/min), tachycardia (HR 162/min), and SpO2 88% on room air. Attempts to pass a nasogastric tube fail at 10-12 cm. Chest X-ray reveals coiling of the tube in the proximal esophagus with no gastric air bubble. No cardiac murmur is auscultated. Which embryologic abnormality most likely explains this presentation?
- A)Failure of fusion of pleuroperitoneal membranes
- B)Abnormal partitioning of the foregut by the tracheoesophageal septumGABARITO
- C)Failure of recanalization of the laryngeal lumen
- D)Persistence of the urachus
- E)Abnormal migration of neural crest cells into the conotruncal ridges
Explicação
The most common tracheoesophageal fistula is esophageal atresia with a distal fistula caused by abnormal separation of the foregut into trachea and esophagus. Polyhydramnios occurs because the fetus cannot swallow amniotic fluid, and choking with the first fee... Ver explicação completa e trilha adaptativa →