A 38-year-old man presents with newly diagnosed hypertension (BP 168/104 mmHg, HR 88/min) and muscle weakness. Laboratory studies reveal hypokalemia (K+ 2.9 mEq/L), elevated plasma aldosterone (22 ng/dL), and suppressed plasma renin activity (0.3 ng/mL/hr; normal 0.5-3.5). Serum sodium is normal. Adrenal CT demonstrates a 1.8 cm left adrenal nodule with low attenuation. Which of the following is the most likely diagnosis?
- A)Cushing syndrome
- B)Primary hyperaldosteronism (aldosterone-producing adenoma)GABARITO
- C)Adrenal carcinoma
- D)Secondary hyperaldosteronism
- E)Pheochromocytoma
Explicação
This patient has primary hyperaldosteronism due to aldosterone-producing adenoma (Conn syndrome). The triad of hypertension, hypokalemic metabolic alkalosis, and an elevated aldosterone-to-renin ratio (>20) with suppressed renin activity is pathognomonic. The ... Ver explicação completa e trilha adaptativa →