A 52-year-old man with alcohol use disorder presents with acute pancreatitis. Forty-eight hours after admission, he develops tremors, anxiety, and diaphoresis. Vital signs show BP 158/94 mmHg, HR 118/min, RR 22/min, and temperature 38.2°C. Serum magnesium is 1.2 mg/dL (normal 1.7-2.2). He has no focal neurologic deficits on examination. He then experiences generalized tonic-clonic seizures. Which medication is most appropriate as first-line treatment?

  1. A)Haloperidol monotherapy
  2. B)BenzodiazepinesGABARITO
  3. C)Physostigmine
  4. D)Naloxone
  5. E)Flumazenil

Explicação

Benzodiazepines are first line for alcohol withdrawal because they restore GABAergic tone and reduce the risk of seizures and delirium tremens. Tremor, autonomic instability, and seizures 2 days after stopping alcohol are classic withdrawal findings. Ver explicação completa e trilha adaptativa →

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