A 68-year-old man with hypertension and a 40 pack-year smoking history presents to his primary care physician with a history of two episodes of left-sided facial droop and arm weakness over the past 6 weeks, each lasting 15-25 minutes before completely resolving. He has no residual neurological deficits on examination. Vital signs are BP 156/94 mmHg, HR 86/min, RR 16/min, SpO2 97% on room air. Carotid duplex ultrasound reveals 70% stenosis of the right internal carotid artery with peak systolic velocity of 230 cm/s. MRI of the brain with diffusion-weighted imaging shows no acute infarction and no prior territorial infarcts. Which of the following is the most appropriate next step in management?
- A)Initiate dual antiplatelet therapy with aspirin and clopidogrel and arrange follow-up duplex ultrasound in 6 weeks
- B)Refer for carotid endarterectomy after confirming with CT or MR angiographyGABARITO
- C)Perform transcranial Doppler ultrasound to assess for right-to-left cardiac shunting
- D)Initiate anticoagulation with apixaban and perform cardiac workup including echocardiography and Holter monitoring
- E)Obtain CT angiography of the head and neck followed by carotid artery stenting
Explicação
This patient has symptomatic carotid artery stenosis (70% stenosis with TIAs in the ipsilateral distribution). The NASCET trial demonstrated that carotid endarterectomy provides significant benefit in reducing recurrent stroke risk in patients with 50-99% sten... Ver explicação completa e trilha adaptativa →