A 35-year-old woman presents with palpitations, heat intolerance, and tremor for 3 months. Vital signs show HR 105 bpm, BP 138/72 mmHg, RR 18/min, temp 37.2°C. She denies recent neck pain or radioactive iodine exposure. Laboratory studies reveal suppressed TSH at 0.05 mIU/L and elevated free T4 at 2.8 ng/dL. A researcher identifies immunoglobulins that activate adenylate cyclase in thyroid follicular cells, driving excess thyroid hormone production. Which condition is most strongly associated with these antibodies?

  1. A)Secondary hypothyroidism
  2. B)Hashimoto thyroiditis
  3. C)Graves diseaseGABARITO
  4. D)Subacute thyroiditis
  5. E)Medullary thyroid carcinoma

Explicação

Graves disease is caused by thyroid stimulating immunoglobulins that bind and activate the TSH receptor, increasing cAMP. Ver explicação completa e trilha adaptativa →

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