A 49-year-old man with alcohol use disorder presents with confusion, gait instability, and horizontal nystagmus. Vital signs show BP 128/76, HR 92, RR 16, Temp 37.2°C, SpO2 98%. Thiamine level is low at 28 nmol/L. After thiamine supplementation, his nystagmus resolves, but severe anterograde amnesia and confabulation persist. He denies recent head trauma. Which structure's damage is most associated with his permanent memory impairment?
- A)Occipital cortex
- B)Subthalamic nucleus
- C)Mammillary bodiesGABARITO
- D)Substantia nigra
- E)Cerebellar hemisphere
Explicação
Mammillary bodies is the correct answer because Wernicke-Korsakoff syndrome from thiamine deficiency is associated with mammillary body damage that can lead to persistent amnesia and confabulation. Ver explicação completa e trilha adaptativa →