A 44-year-old woman with chronic constipation has self-medicated with daily over-the-counter stimulant laxatives for 5 years. She presents with abdominal cramping and loose stools. Vital signs: BP 128/82, HR 88, RR 16, Temp 37°C, SpO2 98%. Colonoscopy reveals dark brown pigmentation throughout the colon without masses or ulcerations. Serum electrolytes are normal. Which agent most likely caused these mucosal findings?
- A)BisacodylGABARITO
- B)Lactulose
- C)Psyllium
- D)Polyethylene glycol
- E)Docusate
Explicação
Chronic use of stimulant laxatives such as bisacodyl or senna can cause melanosis coli from pigment laden macrophages. Ver explicação completa e trilha adaptativa →