A 54-year-old woman with recurrent calcium kidney stones and hypertension presents with BP 158/94 mmHg, HR 82 bpm, and serum creatinine 0.9 mg/dL. She is started on a diuretic. After three months, her BP improves to 132/86 mmHg and 24-hour urinary calcium decreases from 320 to 180 mg/day. Serum potassium remains normal at 4.2 mEq/L. Which medication was most likely prescribed?

  1. A)Furosemide
  2. B)Acetazolamide
  3. C)Mannitol
  4. D)Spironolactone
  5. E)HydrochlorothiazideGABARITO

Explicação

Thiazide diuretics inhibit the sodium chloride cotransporter in the distal convoluted tubule and increase calcium reabsorption, thereby reducing urinary calcium excretion. This makes them useful in hypertension and recurrent calcium nephrolithiasis. Ver explicação completa e trilha adaptativa →

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