A 28-year-old woman has had three episodes over 2 years of neurologic dysfunction, including painful loss of vision in one eye, numbness of the right leg, and urinary urgency. Examination now shows brisk reflexes and an extensor plantar response. MRI shows multiple periventricular white matter plaques. Which of the following is the most likely diagnosis?
- A)Multiple sclerosisGABARITO
- B)Acute disseminated encephalomyelitis
- C)Central pontine myelinolysis
- D)Progressive multifocal leukoencephalopathy
- E)Neuromyelitis optica
Explicação
Episodes separated in time and affecting different CNS locations indicate dissemination in time and space, which is the hallmark of multiple sclerosis. Periventricular plaques and upper motor neuron signs support autoimmune CNS demyelination. Ver explicação completa e trilha adaptativa →