A 76-year-old woman with heart failure and atrial fibrillation taking digoxin presents with nausea, vomiting, and yellow-green halos around lights. Vitals: BP 128/76, HR 102 with frequent ectopy, RR 18, SpO2 98% on room air. ECG demonstrates multifocal premature ventricular contractions. Serum digoxin level is 3.2 ng/mL (therapeutic: 0.5–2.0 ng/mL); potassium is 5.8 mEq/L. She denies chest pain. Which treatment is most appropriate for severe digoxin toxicity?
- A)Digoxin-specific antibody fragmentsGABARITO
- B)Atropine only
- C)Calcium gluconate alone
- D)Methylene blue
- E)Protamine sulfate
Explicação
Digoxin toxicity causes gastrointestinal symptoms, visual disturbances, arrhythmias, and often hyperkalemia in severe overdose. Digoxin-specific antibody fragments are indicated for life threatening toxicity and bind free digoxin, allowing reversal of its effe... Ver explicação completa e trilha adaptativa →