A 45-year-old woman presents with progressive hypertension and muscle weakness. Vital signs show BP 168/102 mmHg, HR 88 bpm, RR 14, temp 37°C, SpO2 98%. Laboratory studies reveal potassium 2.8 mEq/L, bicarbonate 32 mEq/L, elevated aldosterone (22 ng/dL), and suppressed plasma renin activity (0.3 ng/mL/hr). Abdominal CT demonstrates a 1.5-cm left adrenal adenoma. Renal function is normal. Which of the following is the most likely diagnosis?
- A)Secondary aldosteronism from renal artery stenosis
- B)Adrenal carcinoma with excessive renin production
- C)Pheochromocytoma with hypertensive crisis
- D)Primary aldosteronism (Conn syndrome)GABARITO
- E)Glucocorticoid-remediable aldosteronism
Explicação
Primary aldosteronism (Conn syndrome) is characterized by high aldosterone with suppressed renin, leading to hypertension, hypokalemia, and metabolic alkalosis. The unilateral adenoma confirms the adenoma subtype. This is the classic presentation. Ver explicação completa e trilha adaptativa →