A 66-year-old man with methicillin-resistant Staphylococcus aureus bacteremia (blood cultures positive for MRSA) receives intravenous vancomycin infusion. Within 10 minutes, he develops flushing, pruritus, and erythema of the face, neck, and upper torso. Vital signs: BP 148/92 mmHg, HR 112 bpm, RR 20/min, Temp 37.2°C, SpO2 98% on room air. He denies dyspnea or angioedema. Which antimicrobial is the most likely cause of this reaction?
- A)Aztreonam
- B)VancomycinGABARITO
- C)Daptomycin
- D)Nafcillin
- E)Linezolid
Explicação
Vancomycin can cause infusion related histamine release known as red man syndrome, characterized by flushing, erythema, and pruritus, especially when given rapidly. Slower infusion and antihistamines reduce risk. The MRSA coverage clue plus the infusion reacti... Ver explicação completa e trilha adaptativa →