A 45-year-old woman with a 15-year history of ulcerative colitis presents to the clinic with progressive fatigue, dyspnea on exertion, and mild jaundice. She denies abdominal pain or diarrhea flares. Vital signs are normal. Laboratory studies show: Hemoglobin: 8.5 g/dL Mean corpuscular volume: 88 fL Reticulocyte count: 8.2% (elevated) Indirect bilirubin: 2.8 mg/dL Direct bilirubin: 0.3 mg/dL LDH: 580 U/L Haptoglobin: <10 mg/dL Direct antiglobulin test (Coombs): Positive Which of the following autoimmune conditions most likely accounts for this patient's clinical presentation?
- A)Primary sclerosing cholangitis with acute cholestasis
- B)Autoimmune hemolytic anemiaGABARITO
- C)Graves disease with thyroid storm
- D)Systemic lupus erythematosus
- E)Drug-induced immune thrombocytopenia
Explicação
This patient presents with classic laboratory findings of autoimmune hemolytic anemia (AIHA): anemia, elevated reticulocyte count (appropriate bone marrow response), elevated indirect bilirubin, elevated LDH, low haptoglobin (consumed in hemolysis), and positi... Ver explicação completa e trilha adaptativa →