A 3-day-old male neonate presents with polyhydramnios noted prenatally and respiratory distress at birth. Examination reveals excessive drooling and inability to pass a nasogastric tube into the stomach. Chest X-ray shows a coiled catheter in the proximal esophagus with air in the stomach. Which of the following embryologic defects best explains this presentation?
- A)Incomplete neural crest cell migration to the enteric nervous system
- B)Failure of the dorsal pancreatic bud to fuse with the ventral pancreatic bud
- C)Failure of foregut lateral plate mesoderm to form the diaphragm
- D)Abnormal migration of the vitelline duct remnant
- E)Failure of the tracheoesophageal septum to divide the foregutGABARITO
Explicação
Tracheoesophageal fistula with esophageal atresia results from incomplete division of the foregut by the tracheoesophageal septum during weeks 4-6. This causes a blind proximal esophageal pouch and an abnormal connection between the distal esophagus and trache... Ver explicação completa e trilha adaptativa →