A 60-year-old man with type 2 diabetes mellitus presents with a fasting glucose of 110 mg/dL but postprandial glucose of 280 mg/dL due to irregular meal timing throughout the day. Vital signs are stable: BP 138/82, HR 78, RR 16, temp 37°C. HbA1c is 7.8%. Physical exam reveals mild central obesity with a BMI of 29 kg/m². He denies hypoglycemic episodes and takes metformin 1000 mg twice daily. His physician prescribes a short-acting insulin secretagogue taken immediately before meals to reduce postprandial glucose excursions. Which drug was most likely prescribed?
- A)Insulin glargine
- B)Metformin
- C)Glyburide
- D)RepaglinideGABARITO
- E)Pioglitazone
Explicação
Repaglinide is a meglitinide with short duration that enhances glucose induced insulin secretion and is especially useful for postprandial hyperglycemia. Its meal associated dosing makes it more flexible than sulfonylureas when meal timing is irregular. Ver explicação completa e trilha adaptativa →