A 62-year-old man with a 50 pack-year smoking history presents with dry mouth, constipation, and progressive proximal leg weakness. He reports strength improves transiently after climbing stairs. Vital signs: BP 138/82, HR 88, RR 16, Temp 37°C, SpO2 98%. Examination shows diminished reflexes that normalize after exercise. Serum calcium is 11.2 mg/dL. There is no sensory loss. Which of the following is the most likely diagnosis?
- A)Guillain Barré syndrome
- B)Lambert Eaton myasthenic syndromeGABARITO
- C)Botulism
- D)Amyotrophic lateral sclerosis
- E)Myasthenia gravis
Explicação
Autonomic symptoms, proximal weakness that improves with repeated use, and reflexes that facilitate after exercise are classic for Lambert Eaton syndrome. This disorder is often paraneoplastic, especially in association with small cell lung carcinoma. Ver explicação completa e trilha adaptativa →