A 16-year-old girl is evaluated for chronic fatigue, bloating, intermittent diarrhea, and poor weight gain. Laboratory studies show iron deficiency anemia. She has a pruritic vesicular rash on the extensor surfaces of her elbows. Duodenal biopsy shows villous atrophy, crypt hyperplasia, and intraepithelial lymphocytosis. Which of the following is the most likely diagnosis?
- A)Tropical sprue
- B)Lactose intolerance
- C)Crohn disease
- D)Whipple disease
- E)Celiac diseaseGABARITO
Explicação
Celiac disease is a gluten sensitive enteropathy associated with HLA-DQ2 and HLA-DQ8 causing malabsorption and dermatitis herpetiformis. Ver explicação completa e trilha adaptativa →