A 44-year-old man with recurrent ventricular arrhythmias is started on an antiarrhythmic medication. Three months later, he presents with fever (38.5°C), arthralgias, and pleuritic chest pain. Vital signs show BP 128/82 mmHg, HR 92 bpm, RR 18/min, SpO2 98% on room air. Laboratory studies reveal positive antinuclear antibodies (ANA 1:320) and elevated ESR. Chest X-ray shows no infiltrates. Which antiarrhythmic drug most likely caused this drug-induced lupus complication?
- A)Adenosine
- B)Esmolol
- C)Lidocaine
- D)ProcainamideGABARITO
- E)Losartan
Explicação
Procainamide is a class Ia antiarrhythmic that can cause drug induced lupus erythematosus, especially with long term use. The development of serositis and arthralgias after antiarrhythmic therapy is classic. Ver explicação completa e trilha adaptativa →