A 52-year-old woman with no prior neurologic history develops asymmetric vision loss, vertigo, and sensory loss in the lower extremities. Laboratory testing shows elevated inflammatory markers and positive aquaporin-4 IgG antibodies. Brain MRI reveals lesions in the optic nerves, brainstem, and spinal cord. Which of the following is the most likely diagnosis?

  1. A)Chronic inflammatory demyelinating polyneuropathy
  2. B)Neuromyelitis optica spectrum disorderGABARITO
  3. C)Sarcoidosis
  4. D)Leber hereditary optic neuropathy
  5. E)Multiple sclerosis

Explicação

Neuromyelitis optica spectrum disorder (NMOSD) presents with recurrent optic neuritis and transverse myelitis. The seropositivity for aquaporin-4 IgG antibodies is highly specific for NMOSD, distinguishing it from MS. The lesions affecting optic nerves, brains... Ver explicação completa e trilha adaptativa →

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