A 34-year-old woman from Brazil presents with fever (38.2°C), multiple ulcerated lesions on her lip and face, and enlarged regional lymph nodes. Vital signs show BP 118/76, HR 92, RR 18, SpO2 98% on room air. Sputum culture demonstrates budding yeast cells with a distinctive "pilot's wheel" appearance from multiple budding scars. Chest X-ray shows no pulmonary infiltrates. She denies immunosuppressive medication use. Which organism is most likely responsible?
- A)Paracoccidioides brasiliensisGABARITO
- B)Cryptococcus neoformans
- C)Histoplasma capsulatum
- D)Coccidioides immitis
- E)Blastomyces dermatitidis
Explicação
Paracoccidioides brasiliensis is endemic to Central and South America, causing chronic mucocutaneous disease with ulcerated oral and facial lesions. The pathognomonic 'pilot's wheel' morphology results from multiple bud scars on the cell surface. Ver explicação completa e trilha adaptativa →