A 6 month old boy has clusters of sudden flexion of the neck, trunk, and extremities shortly after waking. His parents note developmental regression over the past month. EEG shows a chaotic pattern with multifocal spikes and high voltage slow waves. Which of the following is the best initial treatment?
- A)Ethosuximide
- B)Prednisone or ACTHGABARITO
- C)Levetiracetam
- D)Valproic acid
- E)Vigabatrin only for febrile seizures
Explicação
Prednisone or ACTH is correct. Infantile spasms present with flexor or extensor spasms, developmental regression, and hypsarrhythmia on EEG. First line treatment is ACTH or glucocorticoids, with vigabatrin being especially useful when the spasms are associated... Ver explicação completa e trilha adaptativa →