A 67 year old man comes to the emergency department with 90 minutes of crushing substernal chest pain radiating to the left arm. He has hypertension, hyperlipidemia, and a 40 pack year smoking history. ECG shows ST segment elevations in leads V1 to V4. Troponin I is elevated. He undergoes urgent reperfusion but dies 2 days later from cardiogenic shock. Histologic examination of the affected myocardium would most likely show which of the following patterns of tissue injury?
- A)Saponification with chalky white calcium deposits in fat
- B)Enzymatic digestion with loss of tissue architecture and pus formation
- C)Granular amorphous debris surrounded by epithelioid histiocytes
- D)Preserved tissue architecture with intensely eosinophilic anucleate cellsGABARITO
- E)Immune complex deposition in vessel walls with bright pink fibrin like material
Explicação
Acute ischemic infarction of most solid organs, including the heart, causes coagulative necrosis. The vignette points to an acute anterior wall myocardial infarction, and the hallmark is preservation of the basic tissue architecture for several days with eosin... Ver explicação completa e trilha adaptativa →