A 19-year-old woman presents to the emergency department after intentional propranolol overdose. Vital signs show BP 78/52 mmHg, HR 38 bpm, RR 16, temperature 37°C, and SpO2 98% on room air. Physical examination reveals altered mental status and cool extremities. Serum glucose is 45 mg/dL. She denies chest pain. Which pharmacologic intervention is most appropriate for managing her severe toxicity?
- A)Desmopressin
- B)Atropine eye drops
- C)Flumazenil
- D)GlucagonGABARITO
- E)Pyridostigmine
Explicação
Glucagon is useful in beta blocker overdose because it increases intracellular cAMP independent of beta adrenergic receptors, improving heart rate and contractility. This is a classic toxicology association. Ver explicação completa e trilha adaptativa →