A 34-year-old woman presents to the emergency department with severe vaginal bleeding and easy bruising. Laboratory studies show PT 18 seconds (normal 11-13), aPTT 45 seconds (normal 25-35), platelet count 450,000/μL, and fibrinogen 85 mg/dL (normal 200-400). She denies family history of bleeding disorders. Which of the following is the most likely diagnosis?

  1. A)Thrombotic thrombocytopenic purpura
  2. B)Von Willebrand disease
  3. C)Vitamin K deficiency
  4. D)Hemophilia A
  5. E)Disseminated intravascular coagulationGABARITO

Explicação

DIC presents with consumption of multiple clotting factors and platelets, leading to prolonged PT and aPTT with thrombocytopenia and low fibrinogen. The clinical picture of severe bleeding with lab abnormalities in all three parameters is classic for DIC. Ver explicação completa e trilha adaptativa →

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