A 32-year-old man with a history of hypertension treated with metoprolol presents unresponsive with pinpoint pupils, bradypnea (8 breaths/min), and decreased bowel sounds. Vital signs show BP 88/54 mmHg, HR 42 bpm, temperature 35.8°C, and SpO2 78% on room air. Serum glucose is 89 mg/dL. After administration of a specific antagonist, he rapidly becomes alert with improved respiratory effort (22 breaths/min) and HR increases to 68 bpm. Which drug was most likely administered?

  1. A)Buprenorphine
  2. B)Methadone
  3. C)Atropine
  4. D)Flumazenil
  5. E)NaloxoneGABARITO

Explicação

Naloxone is a competitive opioid receptor antagonist that rapidly reverses opioid induced respiratory depression, miosis, and decreased consciousness. It is first line in suspected opioid overdose. Ver explicação completa e trilha adaptativa →

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