A 16-year-old boy undergoes emergency appendectomy. Shortly after induction with succinylcholine and sevoflurane, he develops rapidly increasing end-tidal CO2 (8.5 kPa), generalized muscle rigidity, and tachycardia (HR 156/min). Core temperature is 40.2°C. Blood pressure is 158/92 mmHg; oxygen saturation remains 98% on 100% FiO2. He has no prior anesthetic complications or family history of adverse reactions. Which agent is most appropriate for immediate treatment?
- A)Atropine
- B)Methylene blue
- C)Naloxone
- D)DantroleneGABARITO
- E)Neostigmine
Explicação
This patient has malignant hyperthermia, a life threatening reaction triggered by succinylcholine and volatile anesthetics. Dantrolene is the treatment because it inhibits calcium release from the sarcoplasmic reticulum by blocking the ryanodine receptor in sk... Ver explicação completa e trilha adaptativa →