A 44-year-old man with chronic hepatitis B infection presents with progressive bilateral lower extremity edema and frothy urine for 3 weeks. Vital signs: BP 148/92 mmHg, HR 88/min, RR 16/min, Temp 37°C, SpO2 98% on room air. Serum albumin is 2.1 g/dL. Urinalysis shows 3+ proteinuria without hematuria. Nephrotic-range proteinuria is confirmed on 24-hour urine collection. Which glomerular disease is most likely responsible?
- A)Membranous nephropathyGABARITO
- B)Anti-GBM disease
- C)Alport syndrome
- D)Minimal change disease
- E)Acute postinfectious glomerulonephritis
Explicação
Hepatitis B is a classic secondary cause of membranous nephropathy, which presents with nephrotic syndrome due to subepithelial immune complex deposition. The adult age, chronic HBV infection, and heavy proteinuria fit this association well. Ver explicação completa e trilha adaptativa →