A 62-year-old man presents to the clinic with a 6-month history of hesitancy, weak urinary stream, and nocturia 3-4 times per night. He denies dysuria, hematuria, or abdominal pain. Vital signs are within normal limits. Digital rectal examination reveals a smooth, enlarged prostate without nodules. Postvoid residual volume by bladder ultrasound is 185 mL. Urinalysis is normal. Serum creatinine is 1.0 mg/dL. The patient is not taking any medications. Which of the following agents would be most appropriate for initial pharmacologic management of his symptoms?
- A)Bethanechol
- B)Atropine
- C)Pilocarpine
- D)DoxazosinGABARITO
- E)Oxybutynin
Explicação
Doxazosin is an alpha-1 adrenergic antagonist indicated for symptomatic relief of lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH). Alpha-1 antagonists relax smooth muscle in the bladder neck and prostate, reducing outlet obstruc... Ver explicação completa e trilha adaptativa →