A 25-year-old male and his wife go to a fertility clinic for evaluation. His wife has no significant past medical history and is given a 'clean bill of health.' He has had bronchiectasis and a history of recurrent sinusitis, and was diagnosed with situs inversus as a child. He is found to be sterile. What is the most likely cause of his infertility?

1. A)Abnormal levels of sphingomyelinase
2. B)Hexosaminidase A deficiency
3. C)Abnormal structure of ciliaGABARITO
4. D)47, XXY karyotype
5. E)Fibrillin deficiency