A 42-year-old man with a history of smoking and COPD presents with hemoptysis and a cavitary lesion in the lung. Culture of sputum grows a dimorphic fungus that appears as a mold at room temperature and yeast at 37°C. He is from Ohio. Which of the following is the most likely diagnosis?
- A)Blastomycosis
- B)Aspergillosis
- C)Tuberculosis
- D)HistoplasmosisGABARITO
- E)Coccidioidomycosis
Explicação
Histoplasma capsulatum is dimorphic, endemic to Ohio River valley, causes cavitary pulmonary disease in males with COPD, and demonstrates mold-to-yeast transformation. This presentation is classic for histoplasmosis with hemoptysis. Ver explicação completa e trilha adaptativa →