A 42-year-old woman with refractory Graves disease presents with tachycardia (HR 118/min), tremor, and heat intolerance. She began propylthiouracil one month ago. Pre-operative labs show TSH 0.1 mIU/L and free T4 8.2 ng/dL (still elevated). Her blood pressure is 148/92 mmHg. Before scheduled thyroidectomy, an additional agent is prescribed to acutely block thyroid hormone release and decrease gland vascularity. She denies iodine allergy. Which drug was most likely added?
- A)Potassium iodideGABARITO
- B)Radioactive iodine
- C)Propylthiouracil
- D)Levothyroxine
- E)Methimazole
Explicação
Iodide acutely inhibits release of preformed thyroid hormone and decreases thyroid gland vascularity, which is helpful before thyroid surgery. It should be given only after a thionamide is started to avoid providing new substrate for hormone synthesis. Ver explicação completa e trilha adaptativa →