A 45-year-old man with a 15-year history of relapsing-remitting multiple sclerosis presents with progressive leg weakness and cognitive decline over the past 2 years without discrete relapses. Brain MRI shows numerous T1 black holes and brain atrophy. Expanded Disability Status Scale score is 6.0. Which of the following best describes his disease course?
- A)Primary progressive multiple sclerosis
- B)Clinically isolated syndrome
- C)Secondary progressive multiple sclerosisGABARITO
- D)Progressive-relapsing multiple sclerosis
- E)Stable relapsing-remitting multiple sclerosis
Explicação
Secondary progressive MS occurs when patients with RRMS transition to a progressive course characterized by steady neurologic decline without discrete relapses. This patient's 15-year RRMS history followed by 2 years of progressive decline, high EDSS score, T1... Ver explicação completa e trilha adaptativa →