A 58-year-old man presents with 8 months of progressive weakness in his hands and legs. Vital signs: BP 128/76, HR 82, RR 16, temp 37°C, SpO2 98%. Examination reveals muscle atrophy, visible fasciculations, hyperreflexia, and spasticity. Sensation remains intact throughout. EMG shows acute denervation potentials and motor unit action potentials. He denies recent weight loss. Which of the following is the most likely diagnosis?
- A)Amyotrophic lateral sclerosisGABARITO
- B)Normal pressure hydrocephalus
- C)Guillain-Barré syndrome
- D)Polymyalgia rheumatica
- E)Myasthenia gravis
Explicação
ALS causes degeneration of both upper and lower motor neurons, leading to mixed findings such as spasticity, hyperreflexia, atrophy, and fasciculations. Sensory function is generally preserved, which helps distinguish it from peripheral neuropathies. Ver explicação completa e trilha adaptativa →