A 19-year-old college student presents to the ED with agitation and altered mental status after ingesting homemade tea from ornamental plant seeds. Vital signs show BP 158/92, HR 128, RR 22, Temp 39.2°C. Physical exam reveals flushed skin, mydriasis, urinary retention, and absent bowel sounds. Serum sodium is 138 mEq/L. He denies previous anticholinergic medication use. Which medication is the most appropriate antidote for this anticholinergic toxidrome?
- A)Naloxone
- B)Atropine
- C)PhysostigmineGABARITO
- D)Flumazenil
- E)Pralidoxime
Explicação
This patient has antimuscarinic toxicity, classically remembered as hot, dry, red, blind, and mad. Physostigmine is a reversible acetylcholinesterase inhibitor that crosses the blood brain barrier and can reverse both central and peripheral antimuscarinic effe... Ver explicação completa e trilha adaptativa →