A 1 day old male newborn develops coughing, cyanosis, and emesis during his first feeding. The pregnancy was complicated by polyhydramnios. Physical examination shows excessive oral secretions and abdominal distension. A nasogastric tube cannot be advanced into the stomach. Which of the following embryologic abnormalities is the most likely explanation for this infant's condition?

  1. A)Failure of tracheoesophageal septationGABARITO
  2. B)Abnormal migration of neural crest cells into the aortic arches
  3. C)Failure of bronchial bud branching
  4. D)Persistence of the pleuroperitoneal membranes
  5. E)Failure of laryngotracheal diverticulum formation

Explicação

Failure of tracheoesophageal septation is correct. The combination of polyhydramnios, drooling, inability to pass a nasogastric tube, and cyanosis with feeding is classic for esophageal atresia with distal tracheoesophageal fistula. This results from abnormal ... Ver explicação completa e trilha adaptativa →

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