A 47-year-old woman presents with a 3-week history of progressive weight loss and palpable purpura on her lower extremities. She develops abrupt left wrist drop followed 2 weeks later by right foot drop. Vital signs show BP 138/88, HR 92, temp 37.2°C, and normal oxygen saturation. Examination reveals asymmetric sensory and motor deficits in separate peripheral nerves. Serum creatinine is normal. Which diagnosis best explains these findings?
- A)Normal pressure hydrocephalus
- B)CIDP
- C)Myasthenia gravis
- D)Mononeuritis multiplexGABARITO
- E)ALS
Explicação
Mononeuritis multiplex causes asynchronous injury to individual peripheral nerves, often from vasculitis, diabetes, or infiltrative disease. The hallmark is asymmetric stepwise deficits affecting noncontiguous nerves such as wrist drop and foot drop. Ver explicação completa e trilha adaptativa →