A 250-bed community hospital implements a new computerized physician order entry (CPOE) system with real-time drug interaction alerts to reduce medication errors in the intensive care unit. Before implementation, a retrospective chart review over 6 months identified 36 medication errors among 800 ICU admissions (4.5% error rate). Three months after CPOE deployment, the quality improvement team reviews 750 ICU admissions and identifies 18 medication errors (2.4% error rate). Patient outcomes remain stable with no increase in adverse drug events, hospital-acquired infections, or length of stay. Which of the following methods is most appropriate for determining whether this CPOE intervention has achieved a sustained reduction in medication errors?

1. A)Survey prescribers and nurses regarding their confidence in the new medication ordering system
2. B)Calculate the return on investment by comparing system implementation costs to prevented adverse events
3. C)Compare pre- and post-implementation medication error rates using statistical process control charts (run charts or control charts) to assess for sustained improvementGABARITO
4. D)Count the number of drug interaction alerts triggered by the CPOE system during the intervention period
5. E)Assess rates of alert fatigue by tracking how often clinicians override automated safety alerts