A 29-year-old woman presents with worsening diplopia and dysphagia by day's end. Vital signs show BP 118/76 mmHg, HR 82/min, RR 16/min, temp 37°C, SpO2 98% on room air. Examination reveals bilateral ptosis that increases with sustained upgaze; strength is normal. Serum anti-acetylcholine receptor antibodies are positive. Reflexes and sensation remain intact. Which of the following is the most likely diagnosis?
- A)Amyotrophic lateral sclerosis
- B)Myasthenia gravisGABARITO
- C)Multiple sclerosis
- D)Lambert Eaton myasthenic syndrome
- E)Botulism
Explicação
Fatigable ocular and bulbar weakness with normal sensation and reflexes is typical of myasthenia gravis. The disorder is caused by antibodies directed against postsynaptic nicotinic acetylcholine receptors at the neuromuscular junction. Ver explicação completa e trilha adaptativa →