A 32-year-old pregnant woman at 28 weeks gestation is concerned about her female fetus inheriting glucose-6-phosphate dehydrogenase (G6PD) deficiency. Her 6-year-old son has the disease with documented enzyme activity of 2 U/g Hb (normal: 6-15 U/g Hb). The father is clinically normal with normal G6PD levels. The mother is asymptomatic with intermediate enzyme activity. Prenatal ultrasound shows normal fetal development. Which statement most accurately describes the inheritance pattern and likely status of her female fetus?

  1. A)The baby has a 50% chance of being a carrierGABARITO
  2. B)The baby has a 25% chance of clinical disease
  3. C)The baby will be a carrier
  4. D)The baby has a 50% chance of clinical disease
  5. E)The baby will have clinical disease

Explicação

The correct answer is B. Source: Kaplan USMLE Step 1 QBank — Biochemistry Test 1. Ver explicação completa e trilha adaptativa →

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