A 52 year old man comes to the office because his wedding ring and shoes no longer fit. He also reports headaches, increased sweating, and hand numbness at night. Examination shows prognathism, frontal bossing, and enlarged hands. Which of the following is the best initial laboratory test to confirm the suspected diagnosis?
- A)Urinary catecholamine metabolites
- B)Low dose dexamethasone suppression test
- C)Serum insulin like growth factor 1 levelGABARITO
- D)Serum prolactin level
- E)Random growth hormone level
Explicação
Acromegaly is usually due to a growth hormone secreting pituitary adenoma. Because growth hormone secretion is pulsatile, insulin like growth factor 1 is the best initial screening or confirmatory laboratory marker, as it integrates growth hormone activity ove... Ver explicação completa e trilha adaptativa →