A 6-year-old boy presents with three weeks of progressive fatigue, fever, and bilateral leg pain. Vital signs: temperature 38.5°C, heart rate 118/min, blood pressure 95/60 mmHg, respiratory rate 22/min. Examination reveals pallor, petechiae, and generalized lymphadenopathy. Laboratory studies show hemoglobin 7.2 g/dL, platelets 35,000/μL, and WBC 52,000/μL with 85% lymphoblasts that are TdT positive. No hepatosplenomegaly is noted. Which of the following is the most likely diagnosis?
- A)Acute myeloid leukemia
- B)Chronic lymphocytic leukemia
- C)Acute lymphoblastic leukemiaGABARITO
- D)Hodgkin lymphoma
- E)Hairy cell leukemia
Explicação
Acute lymphoblastic leukemia is correct. ALL is the most common childhood leukemia and presents with bone marrow failure, bone pain, and lymphadenopathy. Lymphoblasts are typically TdT positive, reflecting immature lymphoid precursors. Ver explicação completa e trilha adaptativa →